By Clare Wilson Would you have pig cells implanted in your brain? Some people with Parkinson’s disease have, in the hope it will stop their disease progressing. The approach is still in the early stages of testing, but initial results from four people look promising, with all showing some improvement 18 months after surgery. People with Parkinson’s disease, which causes tremors and difficulty moving, usually get worse over time. The disease is caused by the gradual loss of brain cells that make dopamine, a compound that helps control our movements. Current medicines replace the missing dopamine, but their effectiveness wears off over the years. So Living Cell Technologies, based in Auckland, New Zealand, has been developing a treatment that uses cells from the choroid plexus in pigs. This brain structure makes a cocktail of growth factors and signalling molecules known to help keep nerve cells healthy. Last month, surgery was completed on a further 18 people in a placebo-controlled trial, using the choroid plexus cell implants. The hope is that compounds made by these cells will nourish the remaining dopamine-producing cells in the patients’ brains, slowing further loss. © Copyright New Scientist Ltd.

Keyword: Parkinsons; Stem Cells
Link ID: 23731 - Posted: 06.12.2017

By JANE E. BRODY Hurray for the HotBlack Coffee cafe in Toronto for declining to offer Wi-Fi to its customers. There are other such cafes, to be sure, including seven of the eight New York City locations of Café Grumpy. But it’s HotBlack’s reason for the electronic blackout that is cause for hosannas. As its president, Jimson Bienenstock, explained, his aim is to get customers to talk with one another instead of being buried in their portable devices. “It’s about creating a social vibe,” he told a New York Times reporter. “We’re a vehicle for human interaction, otherwise it’s just a commodity.” What a novel idea! Perhaps Mr. Bienenstock instinctively knows what medical science has been increasingly demonstrating for decades: Social interaction is a critically important contributor to good health and longevity. Personally, I don’t need research-based evidence to appreciate the value of making and maintaining social connections. I experience it daily during my morning walk with up to three women, then before and after my swim in the locker room of the YMCA where the use of electronic devices is not allowed. The locker room experience has been surprisingly rewarding. I’ve made many new friends with whom I can share both joys and sorrows. The women help me solve problems big and small, providing a sounding board, advice and counsel and often a hearty laugh that brightens my day. © 2017 The New York Times Company

Keyword: Stress
Link ID: 23730 - Posted: 06.12.2017

By David Noonan Sight and hearing get all the glory, but the often overlooked and underappreciated sense of smell—or problems with it—is a subject of rapidly growing interest among scientists and clinicians who battle Alzheimer’s and Parkinson’s diseases. Impaired smell is one of the earliest and most common symptoms of both, and researchers hope a better understanding will improve diagnosis and help unlock some of the secrets of these incurable conditions. The latest offering from the burgeoning field is a paper published this month in Lancet Neurology. It proposes neurotransmitter dysfunction as a possible cause of smell loss in a number of neurodegenerative diseases, including Alzheimer’s and Parkinson’s. More than 90 percent of Parkinson’s patients report some level of olfactory dysfunction. And because problems with smell progress in Alzheimer’s, nearly all of those diagnosed with moderate to severe forms of the illness have odor identification issues. “It’s important, not just because it’s novel and interesting and simple but because the evidence is strong,” says Davangere Devanand, a professor of psychiatry and neurology at Columbia University. His most recent paper on the subject, a review, was published in The American Journal of Geriatric Psychiatry in December. Studies have shown impaired smell to be even stronger than memory problems as a predictor of cognitive decline in currently healthy adults. It is especially useful for forecasting the progression from mild cognitive impairment (MCI) to full-blown Alzheimer’s. According to the Alzheimer’s Association, approximately 15 to 20 percent of people over 65 have MCI. About half of them go on to develop Alzheimer’s, Devanand says—and the sooner they are identified, the earlier doctors can begin interventions, including treatment with the few existing Alzheimer’s drugs. © 2017 Scientific American

Keyword: Alzheimers; Chemical Senses (Smell & Taste)
Link ID: 23729 - Posted: 06.12.2017

By STEPH YIN European eels are born and die in the North Atlantic Ocean, but spend most of their lives in rivers or estuaries across Europe and North Africa. In between, they traverse thousands of miles of ocean, where it’s often unclear which way is up or down. Scientists have therefore long suspected that these critically endangered fish use magnetism to help guide them. A study published Friday in Science Advances shows, for the first time, that European eels might link magnetic cues with the tides to navigate. Studying juveniles during the crucial stage when they move toward land from open ocean, the authors found that eels faced different directions based on whether the tide was flowing in (flood tide) or out (ebb tide). Changing orientation might help eels take advantage of tides to travel from the ocean to the coast, and into fresh water, more efficiently, said Alessandro Cresci, a graduate student at the University of Miami and lead author of the study. Previous studies have shown that eels can detect magnetic fields, but how they use this sixth sense “has remained a matter of speculation” until now, said Michael J. Miller, an eel biologist at Nihon University in Japan who was not involved in the study. When transitioning from sea to coast, European eels are in a stage of their lives where they are about the size of a finger and transparent along their bodies, thus the name “glass eels.” Mr. Cresci’s group studied glass eels from the coast of Norway, observing the animals in the field by putting 54 slippery, see-through eels, one by one, in a drifting chamber equipped with cameras and compasses. When the tide ebbed, these animals generally faced south, but when it flowed in, they showed no consistent orientation. The researchers then studied 49 of the same eels in laboratory tanks. They subjected some of the eels to reoriented magnetic fields, rotating magnetic north to the east, south or west. © 2017 The New York Times Company

Keyword: Animal Migration
Link ID: 23728 - Posted: 06.12.2017

By RICHARD SANDOMIR Isabelle Rapin, a Swiss-born child neurologist who helped establish autism’s biological underpinnings and advanced the idea that autism was part of a broad spectrum of disorders, died on May 24 in Rhinebeck, N.Y. She was 89. The cause was pneumonia, said her daughter Anne Louise Oaklander, who is also a neurologist. “Calling her one of the founding mothers of autism is very appropriate,” said Dr. Thomas Frazier II, a clinical psychologist and chief science officer of Autism Speaks, an advocacy group for people with autism and their families. “With the gravity she carried, she moved us into a modern understanding of autism.” Dr. Rapin (pronounced RAP-in) taught at the Albert Einstein College of Medicine in the Bronx and over a half-century there built a reputation for rigorous scholarship. She retired in 2012 but continued working at her office and writing journal papers. The neurologist Oliver Sacks, a close friend and colleague, called her his “scientific conscience.” In his autobiography, “On the Move: A Life” (2015), Dr. Sacks wrote: “Isabelle would never permit me, any more than she permitted herself, any loose, exaggerated, uncorroborated statements. ‘Give me the evidence,’ she always says.” Dr. Rapin’s focus on autism evolved from her studies of communications and metabolic disorders that cause mental disabilities and diminish children’s ability to navigate the world. For decades she treated deaf children, whose difficulties in communicating limited their path to excelling in school and forced some into institutions. “Communications disorders were the overarching theme of my mother’s career,” Dr. Oaklander said in an interview. In a short biography written for the Journal of Child Neurology in 2001, Dr. Rapin recalled a critical moment in her work on autism. “After evaluating hundreds of autistic children,” she wrote, “I became convinced that the report by one-third of parents of autistic preschoolers, of a very early language and behavioral regression, is real and deserving of biologic investigation.” © 2017 The New York Times Company

Keyword: Autism
Link ID: 23727 - Posted: 06.12.2017

Maria Temming Fascination with faces is nature, not nurture, suggests a new study of third-trimester fetuses. Scientists have long known that babies like looking at faces more than other objects. But research published online June 8 in Current Biology offers evidence that this preference develops before birth. In the first-ever study of prenatal visual perception, fetuses were more likely to move their heads to track facelike configurations of light projected into the womb than nonfacelike shapes. Past research has shown that newborns pay special attention to faces, even if a “face” is stripped down to its bare essentials — for instance, a triangle of three dots: two up top for eyes, one below for a mouth or nose. This preoccupation with faces is considered crucial to social development. “The basic tendency to pick out a face as being different from other things in your environment, and then to actually look at it, is the first step to learning who the important people are in your world,” says Scott Johnson, a developmental psychologist at UCLA who was not involved in the study. Using a 4-D ultrasound, the researchers watched how 34-week-old fetuses reacted to seeing facelike triangles compared with seeing triangles with one dot above and two below. They projected triangles of red light in both configurations through a mother’s abdomen into the fetus’s peripheral vision. Then, they slid the light across the mom’s belly, away from the fetus’s line of sight, to see if it would turn its head to continue looking at the image. |© Society for Science & the Public 2000 - 2017

Keyword: Development of the Brain; Attention
Link ID: 23726 - Posted: 06.09.2017

Rob Stein The Food and Drug Administration requested Thursday that the drugmaker Endo Pharmaceuticals stop selling Opana ER — its extended-release version of Opana. The FDA says the move marks the first time the agency has taken steps to remove an opioid from the market because of "public health consequences of abuse." An increasing number of people, the FDA says, are abusing the powerful prescription pills by crushing, dissolving and injecting them. The sharing of needles by these drug users has fueled an outbreak of associated infectious diseases — HIV, hepatitis C and another serious blood disorder. "We are facing an opioid epidemic — a public health crisis, and we must take all necessary steps to reduce the scope of opioid misuse and abuse," says Dr. Scott Gottlieb, the FDA's commissioner, in announcing the move. "We will continue to take regulatory steps when we see situations where an opioid product's risks outweigh its benefits, not only for its intended patient population but also in regard to its potential for misuse and abuse," Gottlieb says. Dangers Of Opana Opioid Painkiller Outweigh Benefits, FDA Panel Says In a written statement, Endo says the company is "reviewing the request and is evaluating the full range of potential options as we determine the appropriate path forward." The company defended its drug, a version of the medicine oxymorphone hydrochloride, citing the opioid's effectiveness in alleviating pain and Endo's efforts to prevent abuse. © 2017 npr

Keyword: Drug Abuse; Pain & Touch
Link ID: 23725 - Posted: 06.09.2017

By PHILIP S. GUTIS My husband, Tim, and a duo of Jack Russell terriers arrived in my life 13 years ago. They were a package deal that included Osceola Jack, a champion Frisbee player who once was the Mighty Dog actor in the famous commercials, and his pup, the equally mighty Samantha. Later our family grew with Beatrice, a sweet cattle dog mix from Florida who belonged to Tim’s brother but needed a new home. As an introvert, I have not always had the best people skills, but my ability to connect with animals has never flagged. Many of my best memories involve animals. But now things are changing. Last summer, at age 54, I learned I had early onset Alzheimer’s. Amid the many worries that accompany this diagnosis, I am afraid that I will lose my cherished ability to bond with — or even remember — my animal companions much longer. Since my 20s and 30s, I’ve had some weird memory gaps. I once forgot that a childhood best friend worked for me at the school newspaper at Penn State. I wrote off these memory holes to a busy life and career. I worked long days, spent hours on airplanes and trains, managed dozens of people and grappled with complicated issues. I told myself that all of that work, stress and the sheer volume of information that I was expected to retain had to take a toll on my ability to remember everything. But a few years ago, I started to notice that I just wasn’t performing as well as I used to. Keeping track of big projects became increasingly difficult. Skills that were sometimes challenging (simple math, remembering names, understanding maps and directions) became all but impossible. Some days my memory was so bad that I wanted to wear a shirt that said, “Sorry, I just cannot remember your name.” My sister found an online advertisement for people concerned about memory loss. I called the phone number and scheduled an in-person screening. Bring someone familiar with you, the woman on the phone said. I brought Tim, who stayed close as a neurologist poked and prodded me, and vials and vials of blood were drawn. And then came the memory tests. © 2017 The New York Times Company

Keyword: Alzheimers
Link ID: 23724 - Posted: 06.09.2017

Ian Sample Science editor Fossils recovered from an old mine on a desolate mountain in Morocco have rocked one of the most enduring foundations of the human story: that Homo sapiens arose in a cradle of humankind in East Africa 200,000 years ago. Archaeologists unearthed the bones of at least five people at Jebel Irhoud, a former barite mine 100km west of Marrakesh, in excavations that lasted years. They knew the remains were old, but were stunned when dating tests revealed that a tooth and stone tools found with the bones were about 300,000 years old. Why we're closer than ever to a timeline for human evolution Read more “My reaction was a big ‘wow’,” said Jean-Jacques Hublin, a senior scientist on the team at the Max Planck Institute for Evolutionary Anthropology in Leipzig. “I was expecting them to be old, but not that old.” Hublin said the extreme age of the bones makes them the oldest known specimens of modern humans and poses a major challenge to the idea that the earliest members of our species evolved in a “Garden of Eden” in East Africa one hundred thousand years later. “This gives us a completely different picture of the evolution of our species. It goes much further back in time, but also the very process of evolution is different to what we thought,” Hublin told the Guardian. “It looks like our species was already present probably all over Africa by 300,000 years ago. If there was a Garden of Eden, it might have been the size of the continent.” © 2017 Guardian News and Media Limited

Keyword: Evolution
Link ID: 23723 - Posted: 06.08.2017

By Anil Ananthaswamy A machine-learning algorithm has analysed brain scans of 6-month-old children and predicted with near-certainty whether they will show signs of autism when they reach the age of 2. The finding means we may soon be able to intervene before symptoms appear, although whether that would be desirable is a controversial issue. “We have been trying to identify autism as early as possible, most importantly before the actual behavioural symptoms of autism appear,” says team member Robert Emerson of the University of North Carolina at Chapel Hill. Previous work has identified that bundles of nerve fibres in the brain develop differently in infants with older siblings with autism from how they do in infants without this familial risk factor. The changes in these white matter tracts in the brain are visible at 6 months. For the new study, Emerson and his team did fMRI brain scans of 59 sleeping infants, all of whom were aged 6 months and had older siblings with autism, which means they are more likely to develop autism themselves. The scans collected data from 230 brain regions, showing the 26,335 connections between them. When the team followed-up with the children at the age of 2, 11 had been diagnosed with an autism-like condition. The team used the brain scans from when the babies were 6 months old and behavioural data from when the children were 2 years old to train a machine-learning program to identify any brain connectivity patterns that might be linked to later signs of autism, such as repetitive behaviour, difficulties with language, or problems relating socially to others. © Copyright New Scientist Ltd.

Keyword: Autism; Brain imaging
Link ID: 23722 - Posted: 06.08.2017

By LISA SANDERS, M.D. She didn’t have any urgent medical problems, the woman told Dr. Lori Bigi. She was there because she had moved to Pittsburgh and needed a primary-care doctor. Bigi, an internist at the University of Pittsburgh Medical Center, quickly eyed her new patient. She was 31 and petite, just over five feet tall and barely 100 pounds. And she looked just as she described herself, pretty healthy. Doctors often rely on patients’ sense of their well-being, especially when their assessment matches their appearance. But as Dr. Bigi was reminded that day, patients aren’t always right. The patient did say that she had seen her old doctor for awful headaches she got occasionally. They felt like an ice pick through the top of her head, the patient explained, which, at least initially, usually came on while she was going to the bathroom. The headache didn’t last long, but it was intensely painful. Her previous doctor thought it was a type of migraine. He prescribed medication, but it didn’t help. Now her main problem was anxiety, and she saw a psychiatrist for that. Sudden Panic Anxiety is common enough, and because the patient was seeing a specialist, Bigi wasn’t planning to spend much time discussing it. But then the doctor saw that in addition to taking an antidepressant — a recommended treatment for anxiety — the patient was on a sedating medication called clonazepam. It wasn’t a first-line medication for anxiety, and this tiny woman was taking a huge dose of it. The young woman explained that for most of her life, she was not a particularly anxious person. Then, two years earlier, she started experiencing episodes of total panic for seemingly no reason. At the time she chalked it up to a new job — she worked in a research lab — and the pressures associated with a project they had recently started. But the anxiety never let up. © 2017 The New York Times Company

Keyword: Stress; Hormones & Behavior
Link ID: 23721 - Posted: 06.08.2017

Children born to women with gestational diabetes whose diet included high proportions of refined grains may have a higher risk of obesity by age 7, compared to children born to women with gestational diabetes who ate low proportions of refined grains, according to results from a National Institutes of Health study. These findings, which appear online in the American Journal of Clinical Nutrition, were part of the Diabetes & Women’s Health Study, a research project led by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Gestational diabetes, or high blood sugar during pregnancy, affects about 5 percent of all pregnancies in the United States and may lead to health problems for mothers and newborns. The authors noted that previous studies have linked diets high in refined grains — such as white rice — to obesity, type 2 diabetes and heart disease. The researchers compared records from 918 mother-child pairs who took part in the Danish National Birth Cohort, a study that followed the pregnancies of more than 91,000 women in Denmark. They found that children born to women with gestational diabetes who consumed the most refined grain (more than 156 grams per day) were twice as likely to be obese at age 7, compared to children born to women with gestational diabetes who ate the least amount of refined grain (less than 37 grams per day). The link between maternal grain consumption during pregnancy and obesity by age 7 still persisted when the researchers controlled for factors that could potentially influence the children’s weight — such as physical activity level and consumption of vegetables, fruit and sweets. The authors called for additional studies to confirm their results and to follow children through later childhood, adolescence and adulthood to see if the obesity risk persists later in life.

Keyword: Obesity; Development of the Brain
Link ID: 23720 - Posted: 06.08.2017

By NICHOLAS BAKALAR Chronic pain may be linked to an increasing risk for dementia. Researchers interviewed 10,065 people over 62 in 1998 and 2000, asking whether they suffered “persistent pain,” defined as being often troubled with moderate or severe pain. Then they tracked their health through 2012. After adjusting for many variables, they found that compared with those who reported no pain problems, people who reported persistent pain in both 1998 and 2000 had a 9 percent more rapid decline in memory performance. Moreover, the probability of dementia increased 7.7 percent faster in those with persistent pain compared with those without. The study, in JAMA Internal Medicine, does not prove cause and effect. But chronic pain may divert attention from other mental activity, leading to poor memory, and some studies have found that allaying pain with opioids can lead to cognitive improvements. Still, the lead author, Dr. Elizabeth L. Whitlock, an anesthesiologist at the University of California at San Francisco, acknowledged that treatment with opioids is problematic, and that safely controlling chronic pain is a problem that so far has no satisfactory solution. “I’d encourage clinicians to be aware of the cognitive implications of a simple report of pain,” she said. “It’s a simple question to ask, and the answer can be used to identify a population at high risk of functional and cognitive problems.” © 2017 The New York Times Company

Keyword: Alzheimers; Pain & Touch
Link ID: 23719 - Posted: 06.08.2017

Nicola Davis Drinking even moderate amounts of alcohol can damage the brain and impair cognitive function over time, researchers have claimed. While heavy drinking has previously been linked to memory problems and dementia, previous studies have suggested low levels of drinking could help protect the brain. But the new study pushes back against the notion of such benefits. “We knew that drinking heavily for long periods of time was bad for brain health, but we didn’t know at these levels,” said Anya Topiwala, a clinical lecturer in old age psychiatry at the University of Oxford and co-author of the research. Alcohol is a direct cause of seven ​​forms of cancer, finds study Read more Writing in the British Medical Journal, researchers from the University of Oxford and University College London, describe how they followed the alcohol intake and cognitive performance of 550 men and women over 30 years from 1985. At the end of the study the team took MRI scans of the participants’ brains. None of the participants were deemed to have an alcohol dependence, but levels of drinking varied. After excluding 23 participants due to gaps in data or other issues, the team looked at participants’ alcohol intake as well as their performance on various cognitive tasks, as measured at six points over the 30 year period.

Keyword: Drug Abuse
Link ID: 23718 - Posted: 06.07.2017

Children born to women who had gestational diabetes and drank at least one artificially sweetened beverage per day during pregnancy were more likely to be overweight or obese at age 7, compared to children born to women who had gestational diabetes and drank water instead of artificially sweetened beverages, according to a study led by researchers at the National Institutes of Health. Childhood obesity is known to increase the risk for certain health problems later in life, such as diabetes, heart disease, stroke and some cancers. The study appears online in the International Journal of Epidemiology. According to the study authors, as the volume of amniotic fluid increases, pregnant women tend to increase their consumption of fluids. To avoid extra calories, many pregnant women replace sugar-sweetened soft drinks and juices with beverages containing artificial sweeteners. Citing prior research implicating artificially sweetened beverages in weight gain, the study authors sought to determine if diet beverage consumption during pregnancy could influence the weight of children. “Our findings suggest that artificially sweetened beverages during pregnancy are not likely to be any better at reducing the risk for later childhood obesity than sugar-sweetened beverages,” said the study’s senior author, Cuilin Zhang, Ph.D., in the Epidemiology Branch at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). “Not surprisingly, we also observed that children born to women who drank water instead of sweetened beverages were less likely to be obese by age 7.”

Keyword: Obesity; Development of the Brain
Link ID: 23717 - Posted: 06.07.2017

By JULIA FIERRO A few months ago, I gave a reading at a local bookstore. A small but enthusiastic crowd attended, and I confessed to the audience filled with emerging writers that I had, in my 20s and early 30s, stopped writing for eight years, and that I had accepted I’d never write again. Then someone asked, “How did you return to writing?” I decided to tell the truth: Zoloft. I began flipping light switches on and off (always in fives) in third grade. My frugal parents were aghast at the waste of electricity. I tried to explain. I had to flip the switches. Or else something bad would happen, to me, to them. We were all in danger — my younger brother, my school friends, even my pets. I assumed that my fears were rational and that my school friends were like me, worrying all the time. As my obsessions accumulated, the dread throbbed more insistently, and my rituals became more complex. I counted in fives all day at school, my teeth clicking in time so much my teacher grew annoyed by the sound, and when the last school bell rang, my jaw was sore. My nightly prayers became a chant I had to recite 20, then 50 and, later, 100 times. Now that I am a mother, it astounds me that I was able to hide my rituals from my family — but I felt I had no choice. As the daughter of an Italian immigrant who survived unimaginable horrors — poverty, plague, war, domestic violence, the death of his baby sister because of a lack of basic health care — I heard one word over and over again. “Forte.” Strength. Weakness or, to be more specific, showing or admitting to weakness, seemed both un-Italian and un-American. I was raised in a historic whaling village on Long Island. Every year our grade school class field-tripped to the town museum, where we heard stories about courageous Dutch and English settlers who harpooned and lanced whales before towing them ashore and using their flensing knives to cut blubber into long strips. The stories taught us that America was bedrocked with self-reliance and fortitude.

Keyword: Depression
Link ID: 23716 - Posted: 06.07.2017

By Amina Zafar, CBC News Senator Murray Sinclair suffered a mild stroke 10 years ago, while he was still serving as a justice in Manitoba. He got swift treatment, but says for weeks after even simple tasks left him exhausted. It's a hidden issue many stroke survivors experience, according to a new report. A stroke happens in about one in 10,000 adults under the age of 64, the group says. Sinclair, who experienced his stroke in 2007 at the age of 56, recalls waking up feeling dizzy and fuzzy headed. He had trouble getting into his robes for court and found he was bumping into a desk and doorway. Typing with his left hand was also difficult. Sinclair chalked it up to lack of sleep. After court, he called his family doctor in Winnipeg. The doctor performed a few co-ordination tests, immediately administered Aspirin and sent him to the emergency department where he was diagnosed, treated and released that night with medication and follow-up appointments arranged. "For several weeks thereafter whenever I would do something, if I would just go for a walk or if I would go outside and try to cut the grass, which I couldn't, I would just be too exhausted to finish a task. Or after I'd done a small task I'd just need to lay down or sit down," he recalled in an interview. "Even writing and reading were problematic for a while." ©2017 CBC/Radio-Canada.

Keyword: Stroke
Link ID: 23715 - Posted: 06.07.2017

By Jessica Hamzelou Drinking even small amounts of alcohol when pregnant seems to have subtle effects on how a baby’s face develops – including the shape of their eyes, nose and lips. This isn’t necessarily harmful, though. “We don’t know if the small changes in the children’s facial shape are connected in any way to differences in their development,” says Jane Halliday of the Murdoch Children’s Research Institute in Victoria, Australia, who led the research. “We plan to look at this as the children grow.” Heavy drinking during pregnancy can cause fetal alcohol syndrome, which is characterised by distinctive facial features, such as small eye openings, a short up-turned nose, and a smooth philtrum over the upper lip. Children with this condition are likely to have attention and behavioural disorders, as well as a lower IQ, says Halliday. To find out whether low levels of alcohol consumption, which are more common in pregnancy, might also affect developing fetuses, Halliday’s team studied 1570 women throughout their pregnancies and births. Of these women, 27 per cent said they continued to drink at least some alcohol while pregnant. When the children were 1 year old, Halliday’s team took photos of 415 of the babies’ faces with multiple cameras from different angles. When the team stitched these images together using computer software, the resulting 3D photographs detailed almost 70,000 points on each baby’s face. Analysing these revealed subtle differences in the faces of babies whose mothers had drunk alcohol compared with those whose mothers hadn’t. These included a slightly shorter, more-upturned nose. © Copyright New Scientist Ltd.

Keyword: Development of the Brain; Drug Abuse
Link ID: 23714 - Posted: 06.06.2017

By Nicholette Zeliadt, For 6-year-old Macey, lunchtime at school is not so much a break from reading and math as it is an hour rife with frustration. Here’s how Macey’s mother, Victoria, describes Macey’s typical lunch break: In her special-education classroom an hour north of San Francisco, Macey’s classmates gather at a big square table, chattering away and snatching one another’s food. Macey, meanwhile, is sequestered away at a small white table in a corner, facing a bookshelf. She grabs the handle of a spoon using the palm of her right hand, awkwardly scoops up rice and spills it onto her lap. She wants to be at the big table with her peers, but she sits with an aide away from the other children to minimize distractions while she eats. (Victoria requested that we use her and Macey’s first names only, to protect their privacy.) After lunch, the children spill out onto the playground. Macey, wearing a helmet, trails behind, holding her aide’s hand. She can walk, but she often trips on uneven surfaces and falls over. She tends to misjudge heights, and once pulled a muscle while climbing on playground equipment. When she was 3, she tripped and fell headfirst out of a sandbox, scraping her face, chipping one tooth and dislodging another. Macey has little trouble moving around the house because it has few stairs and her mother never changes the layout of the rooms. Victoria’s biggest concern is that Macey’s movement troubles interfere with her social life. © 2017 Scientific American,

Keyword: Autism; Movement Disorders
Link ID: 23713 - Posted: 06.06.2017

By JOSH KATZ AKRON, Ohio — Drug overdose deaths in 2016 most likely exceeded 59,000, the largest annual jump ever recorded in the United States, according to preliminary data compiled by The New York Times. The death count is the latest consequence of an escalating public health crisis: opioid addiction, now made more deadly by an influx of illicitly manufactured fentanyl and similar drugs. Drug overdoses are now the leading cause of death among Americans under 50. Although the data is preliminary, the Times’s best estimate is that deaths rose 19 percent over the 52,404 recorded in 2015. And all evidence suggests the problem has continued to worsen in 2017. Because drug deaths take a long time to certify, the Centers for Disease Control and Prevention will not be able to calculate final numbers until December. The Times compiled estimates for 2016 from hundreds of state health departments and county coroners and medical examiners. Together they represent data from states and counties that accounted for 76 percent of overdose deaths in 2015. They are a first look at the extent of the drug overdose epidemic last year, a detailed accounting of a modern plague. The initial data points to large increases in drug overdose deaths in states along the East Coast, particularly Maryland, Florida, Pennsylvania and Maine. In Ohio, which filed a lawsuit last week accusing five drug companies of abetting the opioid epidemic, we estimate overdose deaths increased by more than 25 percent in 2016. “Heroin is the devil’s drug, man. It is,” Cliff Parker said, sitting on a bench in Grace Park in Akron. Mr. Parker, 24, graduated from high school not too far from here, in nearby Copley, where he was a multisport athlete. In his senior year, he was a varsity wrestler and earned a scholarship to the University of Akron. Like his friends and teammates, he started using prescription painkillers at parties. It was fun, he said. By the time it stopped being fun, it was too late. Pills soon turned to heroin, and his life began slipping away from him. © 2017 The New York Times Company

Keyword: Drug Abuse
Link ID: 23712 - Posted: 06.06.2017