Mariana Lenharo As artificial-intelligence systems become more and more sophisticated, the question of whether they might become conscious is capturing the public’s attention — and is sending tech firms to hire philosophers. The problem is, researchers still haven’t agreed on what gives rise to consciousness in humans, let alone an AI chatbot. So some scientists who study human consciousness — the subjective state of being aware of yourself and your surroundings — worry that all the hype will make it harder to find answers. “What we might see is a sort of capture of consciousness research by the AI sector, where less emphasis is placed on the neuroscience and philosophy of how consciousness happens in real brains, and more on looking for computational ‘signatures’ of consciousness in AI,” says Anil Seth, a consciousness scientist at the University of Sussex near Brighton, UK. Seth and others think that consciousness is very unlikely outside of biological organisms and are frustrated by the focus on AI. Some are suspicious of AI firms’ hype, and think that there should be more investigation of how the humanization of chatbots could affect people negatively. But there are researchers who think that tech firms’ obsession with consciousness is a boon for a field that was not taken seriously as a scientific endeavour for years. They see the hype as bringing more interest and, importantly, more funding. Running into problems Earlier this month, it became clear that determining whether an AI system is sentient will be extremely challenging without knowing more about human consciousness. Researchers at AI firm Anthropic, in San Francisco, California, posted a non-peer-reviewed study suggesting that they had found something in the company’s large language model (LLM) Claude that is comparable to conscious thoughts in humans. By measuring patterns in Claude’s processing, they uncovered words that Claude ‘thought’ about as it worked through a request but did not necessarily include in its output. The authors compare this internal activity with the brain’s ‘global workspace’, a concept borrowed from one of the most popular theories of human consciousness. The global workspace theory (GWT) posits that information enters human consciousness when it is broadcast across the brain, in a type of processing hub for the mind. © 2026 Springer Nature Limited

Keyword: Consciousness
Link ID: 30350 - Posted: 07.29.2026

By Emily Anthes One day last summer, a curious white-faced capuchin encountered a strange contraption in the forest. There, in the middle of the Taboga Forest Reserve in Costa Rica, sat a 15-inch touch screen, mounted in a wooden frame. As the monkey, an alpha male named Papi, began investigating — poking the device here, prodding it there — his fingers landed on the screen. Suddenly, a piece of dried banana dropped into a tray below the frame. Before long, Papi learned the basic rules of the device: touch the screen, get a dried banana slice. He also provided proof of concept for CapuchinAI, a new device designed to assess the cognitive abilities of monkeys in the wild. The testing apparatus, which the researchers described in a new paper, used A.I.-powered facial recognition software to detect capuchins in real time and record their responses to a simple learning task. The scientists hope that more sophisticated versions of the device, which they will begin testing in the coming weeks, will shed new light on primate evolution and intelligence, and answer questions that would be impossible to study in a lab, such as how a monkey’s smarts affect its success and survival. “If we really want to understand how primates make decisions, if we want to understand how they’re using these large brains that they evolved, we have to really put it in the context of the world in which they’re navigating,” said Marcela Benítez, a primatologist at Emory University and an author of the new paper, which was published in the American Journal of Primatology on Tuesday. “But that is a lot easier said than done.” Dr. Benítez has been studying the white-faced capuchins at Taboga for years, logging their behavior, recording their vocalizations and measuring their hormone levels. For the new study, she and her colleagues used images of some of these monkeys to train an artificial intelligence model to identify capuchins and distinguish them from the other animals roaming the forest. Then they built a portable testing station equipped with a touch screen, webcam and 3-D-printed food dispenser. © 2026 The New York Times Company

Keyword: Learning & Memory; Evolution
Link ID: 30349 - Posted: 07.29.2026

Maria Godoy School used to be pretty easy for Kate Jarvis when she was a little girl, back in the 1980s. She was a straight-A student, creative, and so organized that she'd even prep her toothbrush with toothpaste each night before school. She says her mother used to call her "bright-eyed and bushy tailed." Then puberty hit, and everything started to fall apart. She found it harder to focus in school, and her grades slipped. "It really hit my self-esteem badly. I felt pretty awful about myself," she says. In high school, she was diagnosed with anxiety and depression. She struggled to fit in. She says it stung when teachers would write comments like, "Kate has so much potential, if only she'd apply herself." "So it felt like character flaws rather than what it really was, which was undiagnosed ADHD," says Jarvis, who didn't get a diagnosis until her late 30s. Kate Jarvis says that her diagnosis of ADHD in her 30s felt revolutionary. “Something I had been wrestling with for 25 years had a name, causes, symptoms and effects.” However, the diagnosis came with challenges as well. “Just because you know what something is, doesn’t mean you can immediately fix it. And that’s what I felt, like I needed to fix myself.” Kate Jarvis says that her diagnosis of ADHD in her 30s felt revolutionary. "Something I had been wrestling with for 25 years had a name, causes, symptoms and effects." However, the diagnosis came with challenges as well. "Just because you know what something is, doesn't mean you can immediately fix it. And that's what I felt - like I needed to fix myself." Jarvis family © 2026 npr

Keyword: ADHD; Sexual Behavior
Link ID: 30348 - Posted: 07.29.2026

By Emily Laber-Warren When sunlight hits an octopus, it can trigger a swift color change and instant camouflage, thanks to light-sensitive molecules embedded in the creature’s skin. When sunlight falls on a bird’s skull, similar compounds deep in the animal’s brain register changes in day length and help drive decisions on when to mate or migrate. Photosensitive proteins called opsins that respond instantly to sunlight can be found within and outside the eye in nearly every animal, and they govern not only vision but also a range of behaviors. Until about a quarter-century ago, though, the scientific consensus was that in humans, the only role for opsins was to help us see. But a surge of research over the past couple of decades has increasingly revealed that, like honeybees, zebra fish, rodents and other creatures, we harbor opsins that aren’t involved in vision, both in our eyes and throughout our bodies. These molecules appear to play a broad role in human biology, affecting mood, metabolism, sleep, thinking and social behavior. Since life’s beginnings, organisms on this sunbaked planet have had to evolve ways to protect against ultraviolet light, which can damage DNA. But it shouldn’t be surprising that, as dangerous as sunlight can be, most animals also rely on it to regulate key aspects of physiology, including body temperature, navigation, growth and sexual development. Across the animal kingdom, researchers are discovering that light-sensing opsins are involved in an array of biological processes beyond vision. These include camouflage; sensing seasonal changes via lengthening or shortening day lengths; synchronizing with the 24-hour cycle — as well as mood, healing and more.

Keyword: Vision; Biological Rhythms
Link ID: 30347 - Posted: 07.29.2026

Max Kozlov How does the brain know when it’s time to wake up? Researchers have identified1 a chemical signal that serves as a timer in the mouse brain, logging both the length of a single sleep session and the number of interruptions and predicting how likely an animal is to wake up at any given moment. This signal could offer a new way to measure ‘sleep debt’, or accumulated sleep loss. Such a biomarker could one day lead to methods for checking whether someone is sleep-deprived, says Ketema Paul, a neuroscientist at the University of California, Los Angeles, who was not involved in the research. “We really don’t have what a lot of people call the sobriety test for sleep,” Paul says, adding that such a test could be useful to ensure that people in high-stakes occupations, such as driving trucks or working in a hospital emergency department, are able to remain alert. “The negative effects of sleep loss can have serious negative consequences.” Previous sleep research has focused mostly on the brain circuitry that snaps people awake in seconds or on how sleep debt accrues after days of bad sleep. But the intermediate time scale — how the brain keeps track of the minutes or hours spent in a single continuous session of sleep — has remained a mystery. To investigate, Yao Chen, a neuroscientist at Washington University in St. Louis, Missouri, and her team searched for molecular signals that shift gradually during a sleep session. The researchers used a specialized fluorescent sensor in the brains of mice to watch, in real time, the effects of protein kinase A, or PKA — an enzyme also found in humans and previously linked to wakefulness2. This enzyme adds chemical ‘tags’ to proteins on the surface of brain cells. © 2026 Springer Nature Limited

Keyword: Sleep; Biological Rhythms
Link ID: 30346 - Posted: 07.29.2026

By Emily Singer It all started at the bar at a Cold Spring Harbor Laboratory meeting more than 10 years ago. A scientist pulled out his iPad and began showing Tyler Sloan, then a neuroscience graduate student, a 3D video that flew through the bundled nerve fibers of the spinal cord in a tissue-cleared embryo. “My first thought when I saw that was that we need to put this on a planetarium dome,” Sloan says. The video reflected a turning point in microscopy imaging, when techniques such as Clarity, which enables high-resolution imaging of intact tissue, made it possible to image relatively large volumes of the brain and illustrate the nervous system’s complexity in all its glory. Inspired by the public engagement he saw at astronomy screenings at planetariums, Sloan wanted to employ these kinds of videos to kindle the same sense of awe toward the brain. He began learning 3D animation, eventually leaving academia and launching his own company to create sophisticated visualizations for scientists. But, he says, it was all in service of his goal to make an immersive brain movie for the public. More than a decade after the idea took root, the project has finally borne fruit: Sloan’s planetarium film premiered during the weeklong BrainFest event in Seattle in March. Other showings are in the works, including at Neuroscience Academy Denmark’s annual meeting in November. Sloan says he plans to make the film freely available and hopes it will eventually be shown at planetariums around the world. Tyler Sloan: We can do a better job of inspiring people with a sense of awe. I went to a national park in Canada with an observatory over spring break with my family. Their outreach is really elaborate; they have an emcee and what they call the cosmic jockey, the technician operating the computer in the background and throwing up images throughout the entire presentation. I was amazed at the level of questions coming from school-aged kids. © 2026 Simons Foundation

Keyword: Brain imaging
Link ID: 30345 - Posted: 07.29.2026

Stephani Sutherland One night in 2000, Allan Basbaum was at the Pierre Hotel on Central Park, wearing a tuxedo after presenting a neuroscience award to one of his colleagues before a roomful of scientists, Nobel laureates among them. His wife, Carol, a cancer biologist, had accompanied him from San Francisco, where they both ran laboratories at the University of California. Late that night, he was struck by agonising stomach pain. Alarmed, they went to the emergency room at Lenox Hill Hospital, where the waiting area was jammed and hours passed before anyone could see him. ‘So I’m out in the waiting room; I’m periodically screaming,’ Basbaum says. After two hours, Carol went to the bathroom, leaving him alone. Finally, a man came over and began speaking to him, gently prodding him. ‘He checks my pulse, he asks: “Does this hurt?”’ Basbaum says. As the man attended to him, ‘the pain really started to get much better,’ and Basbaum relaxed. When Carol returned, he told her about the long-awaited treatment. ‘She says: “Allan, he’s one of the patients. He’s been doing that to everybody here.” But finally, someone was taking care of me.’ And that brought relief. By then, Basbaum had spent three decades studying the physiology of pain, mapping the neural circuits that carry signals from the body toward the brain. He wanted to understand how those signals become pain. His experience brought to life the questions he’d been marvelling at for years: how do fear, context and expectation shape the body’s most urgent alarm? How do placebos work? And how could someone relieve his pain, just by paying attention? Basbaum understood the Gordian knot at the heart of pain: the brain could influence pain before a person consciously felt it. His work over the past 50 years has been to untangle that loop, following signals through the spinal cord to the brain and back again. © Aeon Media Group Ltd. 2012-2026.

Keyword: Pain & Touch; Attention
Link ID: 30344 - Posted: 07.25.2026

By Kristen French Psychedelics get humans high. On this point, there is no question. For centuries, Indigenous shamans, the mystically inclined, and the neuro-curious have been ingesting the trippy stuff to incur strange visions and otherworldly flights. But why psychedelics evolved is less clear and remains the subject of strenuous debate. Tiny amounts of DMT are naturally produced in the brains of humans and other mammals, which has led some neuroscientists and ethnobotanists to argue that hallucination may have some direct evolutionary or therapeutic benefit to humans, that the DMT is there to serve a special visionary or consciousness-related function, and that psychedelic plants may have co-evolved for human spiritual use. But the authors of a new study published in Proceedings of the National Academy of Sciences argue that human hallucination is more likely just a side effect, and that psychedelics probably evolved as ecological tools, allowing various animals and plants to defend against predators and herbivores or to help manage symbiotic relationships. After all, hallucinogens like psilocybin, mescaline, and DMT are extremely common in the animal kingdom, appearing independently in numerous unrelated organisms such as mushrooms, cacti, toads, and sponges. “Understanding why evolution produced these molecules doesn’t diminish their therapeutic value,” wrote study author Yibo Wang, a chemist at the Chinese Academy of Sciences, in an email. “Instead, it provides a deeper biological framework for discovering better medicines while promoting conservation and sustainable production.” Wang and his team propose that humans hallucinate when we ingest psychedelics because we share ancient brain chemistry with the creatures who were the original targets of the compounds, such as slugs, insects, and sea urchins. The receptors these compounds mess with—serotonin, opioid, and GABA receptors—are also found all over the animal kingdom. So the chemicals that scramble human perception may also deter snails from eating certain plants, the researchers suggest. © Copyright 2026

Keyword: Drug Abuse
Link ID: 30343 - Posted: 07.25.2026

By Julia Vaz Kelly Jaakkola spends her time getting dolphins to tell her things. In her observations as a cognitive psychologist at the Dolphin Research Center in Grassy Key, Florida, she’s discovered that the marine mammals cooperate to solve problems, and that they respond to complex human gestures such as pointing. Her colleague Jason Bruck, a biologist at Stephen F. Austin State University, has even shown that dolphins seem to have names for one another, just like humans do. Studies have started to pile up showing that other animals might be able to do the same. But Jaakkola is skeptical. In an opinion piece published today in Cell Press, she, Bruck, and biologist Stephanie King at the University of Bristol argue there is little evidence that other cognitively complex animals such as marmosets and elephants use names. Names, Jaakkola and her co-authors propose, must be learned, they must be shared among members of the community, and they must act as a symbolic representation of a specific individual. Showing that animal calls fulfill all those requirements is more challenging than it seems. Science chatted with Jaakkola about how researchers can test whether animals really use names—and why that matters. This interview has been edited for clarity and length. Q: Names seem simple to us, but they’re actually quite hard to define. Is that right? A: When we talk about names, what we’re talking about is a shared symbolic label that [picks] out a particular individual. So, if you say something is a name, you’re talking about a symbol for something in the world. The way that I typically talk about it is the difference between “Hey, you” and “Hey, Julia.” In both cases, I’m picking out somebody, but only in one case does it actually mean that person. Also, by this definition, names have to be learned, because you can’t be born knowing the names of everybody you’re ever going to meet. © 2026 American Association for the Advancement of Science.

Keyword: Animal Communication; Language
Link ID: 30342 - Posted: 07.25.2026

By Sujata Gupta Some 7,500 languages are spoken or signed around the world today. Though that might sound like a lot, the number could have been up to 10 times higher a few thousand years ago, researchers report July 23 in Science. “That was the golden age of linguistic diversity,” says Claire Bowern, a linguist at Yale University. The finding comes as scientists are racing to document, or ideally preserve, languages nearing extinction. Half of today’s languages are now endangered, and roughly four languages disappear every year. Linguists and cognitive scientists have long sought to identify features of language, whether unique to a given culture or universal, to generate theories about how humans reason about the world. Any underestimate of linguistic diversity would mean those theories are missing a lot of what is possible. But ancient languages are challenging to study. They don’t leave a fossil record. And writing emerged relatively recently — in the past 6,000 years — and among only a subset of languages. So Bowern’s team developed a model to try to quantify what might have happened to language diversity over the past several thousand years, including pinning down when it started to shrink. The team first looked at more than 170 contemporary hunting and gathering groups worldwide as a proxy for past populations. Though such groups have changed across time, many key aspects of their social structure have remained stable, research elsewhere suggests. Chiefly, foraging groups vary in size but typically include several hundred people to more than a thousand. And, broadly speaking, each group speaks a single language. © Society for Science & the Public 2000–2026.

Keyword: Language; Evolution
Link ID: 30341 - Posted: 07.25.2026

By Hannah Docter-Loeb At the otolaryngology department at the Ohio State University, Kai Zhao is on a quest to solve smell loss. While cochlear implants or hearing aids can be used to treat auditory impairments and lenses or surgery can tackle vision loss, there is no equivalent go-to treatment for a weakened sense of smell. Among all the senses, smell is perhaps the least well understood. Scientists are only just beginning to get to grips with how smell is organized in the brain and body. And exactly why and how some people lose their sense of smell is unclear at best. “Smell loss is a really underrecognized problem and medical condition, and currently there [is] no treatment at all,” Zhao says. Some researchers have experimented with bionic noses and implants that pulse electrical signals into the olfactory system to try and restore smell. But Zhao is trying a different method: wearable devices that help redirect airflow in the nose to the olfactory region. Only a fraction of the air we breathe in through our noses reaches the olfactory cleft—that’s the place inside our noses where the olfactory bulb, a structure in the forebrain that processes smell signals, resides. Zhao theorized that perhaps it would be possible to increase the airflow to the olfactory system. He likens the idea to hearing aids, which amplify sound signals in the ears. “You’re amplifying the smell signal instead of the sound,” he says. In March 2025 Zhao and his colleagues published the results of their first prototypes in BMC Medicine. They developed a nasal foam plug and a clip similar to those used by synchronized swimmers. Both work to enhance the odor delivery to the olfactory region. The plug helps open the odor flow to the nose. Meanwhile, according to Zhao, the clip is a bit more counterintuitive: it pinches the nasal valve to enhance narrowing, which can improve function. © 2026 SCIENTIFIC AMERICAN INC.

Keyword: Chemical Senses (Smell & Taste)
Link ID: 30340 - Posted: 07.25.2026

Ushika Kidd Long-term exposure to road traffic noise is associated with a higher risk of Parkinson’s disease, the biggest study of its kind has found. Parkinson’s disease is a progressive disorder in which parts of the brain become damaged over time, affecting movement and balance. Existing research has found potential biological pathways that link noise exposure to Parkinson’s disease, largely due to stress responses and disrupted sleep. The researchers modelled noise exposure at the most and least exposed exterior of the residence of each participant and calculated the difference in noise levels. The magnitude of the effect was modest but consistent; at the most exposed facade, for every 11.5dB rise in noise level, the risk of Parkinson’s disease rose by 3% over the study period. Having a quiet part of the home may mitigate the association between exposure to road traffic noise and higher risk of Parkinson’s disease, according to the findings. The study, published in Jama Neurology, included 3.1 million Danish participants aged 40 and over, and followed them for 18 years. It was established using nationwide health register data, making it the largest study on road traffic noise and Parkinson’s disease. Previous research linked the rise in neurological disorders, including Parkinson’s disease, with exposure to environmental toxins. Environmental risk factors such as air pollution, microplastics and pesticides have become the main focus of prevention strategies. © 2026 Guardian News & Media Limited

Keyword: Parkinsons; Hearing
Link ID: 30339 - Posted: 07.25.2026

Emma Bryce Sperm whales produce a specific pattern of clicking noises when they hear the noise of boats, researchers have found. The pattern is so distinct that the scientists who identified it said they can now use it to predict when ships are nearby. Researchers from Project Ceti (the Cetacean Translation Initiative), a non-profit research organisation working to decode sperm whale communication, spent four years tuning in on the calls of 15 sperm whales off the coast of Dominica. They discovered specific differences in sperm whale “codas”, the discrete and distinctive patterns of clicks that this species utters to communicate when those whales encountered shipping. Individual click sequences became shorter, and one type became more prominent than another. Their findings are published in the journal Ecological Informatics. “This research begs the question: are whales talking about the ships, or is it an impact on their voices because the ships are around?,” said David Gruber, the founder and chief executive of Project Ceti. “And then if we’re able to discern what they’re saying about the ships, how might that impact policy and laws?” Under normal conditions, recordings from one of the whales, named “Atwood”, picked up one type of coda comprising five clicks in a 1-1-3 pattern (two clicks preceding three quicker ones), which, Gruber explained, is unique to this specific clan of sperm whales off the Caribbean coast of Dominica. With the background hum of a ship, Atwood issued the same 1-1-3 click rhythm but noticeably faster, with the whale reducing the intervals between each click. The association was so strong that “in general, from their vocalisations alone, we can predict whether ships are around,” said Gašper Beguš, linguistics lead at Project Ceti. © 2026 Guardian News & Media Limited

Keyword: Animal Communication; Evolution
Link ID: 30338 - Posted: 07.22.2026

By K. R. Callaway You (probably) won’t find a monkey in a geometry class, but it looks like our fellow primates can swing the basics. Just like people, monkeys seem to grasp the abstract qualities of geometric shapes, such as whether they are symmetrical, have parallel sides or contain right angles, according to a new study published on Monday in Proceedings of the National Academy of Sciences. This ability allows the monkeys — and us — to understand when two shapes are the same, even when they’ve been rotated or resized. This finding challenges a long-held notion that humans’ geometric abilities are part of what makes our brains one of a kind. “Our hypothesis was that humans are not that unique,” in possessing this mathematical understanding, said Jialin Li, a cognitive neuroscientist at Carnegie Mellon University and the lead author of the study. In their experiment, Ms. Li and her colleagues decided to give monkeys (a total of eight rhesus macaques and olive baboons), preschoolers and adult humans with different education levels the same geometric task. That way, if humans truly had an innate advantage, it would show up when comparing the young children and the monkeys. And if the advantage was learned, it might show up when comparing the humans who had different levels of schooling. It was a challenge to find a task simple enough that even preschool-aged children and monkeys could reasonably complete it, but the team eventually decided to have all the study participants do a matching task. All were shown a shape with a specific size and geometric form on a screen. Then they were asked to pick that same shape out of a group of others. “By manipulating the similarity of the shapes, we were able to look at what kinds of rules they’re using,” said Jessica Cantlon, a cognitive neuroscientist at Carnegie Mellon University whose lab conducted the study. © 2026 The New York Times Company

Keyword: Vision; Learning & Memory
Link ID: 30337 - Posted: 07.22.2026

Lynne Peeples Every heartbeat is choreographed not just by the brain but also by a mysterious nervous system embedded in the heart itself. Now, scientists studying mice have started to unravel how this complex system works to keep the heart beating steadily even at times of extreme stress — findings that challenge the classic view that all cardiac neurons are alike. “The key is to keep the heart functional no matter what happens. Because if the pump function stops, you will die,” says Rui Chang, a neuroscientist at Yale University School of Medicine in New Haven, Connecticut, and co-author of the new paper. The findings, published today in Cell1, could inform better treatments for heart disease. Like the gut’s widely recognized ‘second brain’, the heart contains a mini-brain of its own — known, more formally, as the intrinsic cardiac nervous system. This network of neurons is embedded in the fat pad surrounding the heart. The system’s neurons exchange messages with the brain and with each other, and are the final players in a long chain of neurons that controls cardiac function. But because intrinsic cardiac neurons are exceedingly rare, making up only about 0.01% of the cells in a piece of heart tissue, their precise roles have been hard to pin down, says Chang. Damage from a heart attack comes from brain signals, mouse study suggests To fill that gap, his team genetically engineered mice to label all of the animals’ cardiac neurons. The scientists sequenced genes isolated from these neurons and identified markers for two neuronal subtypes. They then used techniques such as high-resolution imaging to identify the genetically distinct subtypes’ core functions and to map their locations. © 2026 Springer Nature Limited

Keyword: Emotions
Link ID: 30336 - Posted: 07.22.2026

BY Christie Wilcox Goats spend a lot of time bashing their heads into things. Winning a headbutting contest shows other members of the herd who’s boss—but bumping heads is also a way to play or explore new objects, so it’s often assumed goats must be protected against head injury by the shape of their skull and strong neck muscles. A new study challenges that assumption. Researchers have found early signs of neurodegeneration in headbutting goats at just 1 year old, they report in a preprint posted to bioRxiv this month. The findings, they say, suggest goats could be a useful animal model for studying the link between head injuries and neurodegeneration seen in humans. “I think the overall conclusions are pretty convincing,” says Ramon Diaz-Arrastia, a neurologist at the University of Pennsylvania who was not involved with the work. Traditionally, researchers have used rats and mice as animal models for studying brain injuries, and the field has become a “rodent monoculture,” he says. But rodent and human brains are very different, which could be partly to blame for the poor translation of preclinical findings to human trials, so it’s “really interesting to see this work in goats.” Nicole Ackermans, a neuroscientist at the University of Alabama, first identified signs of neurodegeneration in wild headbutting animals in 2022, finding that the brains of dead muskoxen contained an abnormal version of the protein tau. In humans, these tangled tau proteins are associated with neurodegenerative diseases such as Alzheimer’s, and can form after head injuries. “I thought, ‘OK, this is something really interesting to look at for modeling brain damage,’” she says. But tracking how damage accumulates over time in wild animals is not feasible. That’s where the goats came in. The team acquired three 6-month-old male goats—Alvin, Simon, and Theo—from farms and moved them to a nearby agricultural college where cameras recorded them for 6 months to track their headbutts. Each month, the researchers collected samples of blood, saliva, and brain fluid to look for biomarkers of brain injury and, at the start and end of the study, scanned the animals’ brains using positron emission tomography–MRI to spot any structural damage. © 2026 American Association for the Advancement of Science.

Keyword: Brain Injury/Concussion; Aggression
Link ID: 30335 - Posted: 07.22.2026

By Liz Seegert More than one in 10 Americans takes a GLP-1 medication for weight loss. As more people take a GLP-1, or glucagonlike peptide 1, receptor agonist, such as Wegovy, so, too, do more older adults—and those numbers are set to skyrocket. Last week the Trump administration launched the Medicare GLP-1 Bridge program, a new initiative that would set the cost of three weight-loss medications— Wegovy, the KwikPen version of Zepbound (tirzepatide) and Foundayo (orforglipron)—at $50 a month. That may be welcome news for the estimated 38.9 percent of adults aged 60 and up in the U.S. who are living with obesity. But it could also supercharge an ongoing and risky experiment in growing old on weight-loss drugs. For years, clinicians have had few good options to safely treat obesity in older adults. But while GLP-1s, long used to treat diabetes, are now approved for weight loss, the evidence supporting their use in the age-60-and-older population is limited. Someone in their 70s may benefit as much from weight loss as a person in their 30s but may respond very differently to these drugs’ side effects; we simply don’t have enough evidence yet to make informed conclusions, experts advise. “Eligibility doesn’t mean benefit automatically,” says Ruchi Gaba, an associate professor of endocrinology at Baylor College of Medicine. “We have to individualize.” And within the 60-and-older group, there is huge variety: a healthy, active 68-year-old with obesity and sleep apnea is a very different patient than an 88-year-old who’s frail, has poor appetite and is at risk of falls, Gaba says. Older adults are underrepresented in the clinical trials for GLP-1 drugs. Despite the high prevalence of obesity among this age group, only about one in 10 participants in early GLP-1 trials was age 65 or older, says Alissa Chen, a primary care physician and a researcher at the Yale School of Medicine, who specializes in obesity. Older adults are more heterogeneous than people in younger age groups in terms of chronic conditions and multiple medications, Chen says, which can pose challenges with both prescriptions and side effects. © 2026 SCIENTIFIC AMERICAN

Keyword: Obesity; Development of the Brain
Link ID: 30334 - Posted: 07.22.2026

By Dylan Loeb McClain Susumu Tonegawa, a Japanese molecular biologist who won the Nobel Prize in 1987 for figuring out how the body can produce sufficient antibodies to combat a multitude of infections, and who later advanced the understanding of how the brain works by discovering how memories are stored, died on July 11 at his home in San Mateo, Calif. He was 86. The Massachusetts Institute of Technology, where Dr. Tonegawa was a professor, announced his death. “Few scientists have reshaped our understanding of biology as profoundly,” Myriam Heiman, the director of M.I.T.’s Picower Institute for Learning and Memory, which Dr. Tonegawa founded in 1994, said in a statement. “His intellectual fearlessness, extraordinary creativity and relentless pursuit of fundamental questions opened entirely new frontiers in both immunology and neuroscience.” For decades, scientists were confounded by the antibodies created in the white blood cells known as B lymphocytes. Those antibodies, which fight disease, are shaped like Y’s, with two long and two short symmetrical chains of proteins built from amino acids, all bound together by bridges of sulfur atoms. Most of the long proteins and some of the short ones are considered constants because they are the same in all antibodies. At the end of each strand are variable amino acids that allow the antibodies to bind to antigens on an array of infections, disabling them. A common analogy is that the constant amino acids are like the shaft of a key, and the variable ones are the notches that turn the lock. As with a key, each combination of notches is unique. Even so, scientists were puzzled by how the antibodies could create enough combinations to fight millions of infections. © 2026 The New York Times Company

Keyword: Learning & Memory
Link ID: 30333 - Posted: 07.22.2026

By Elie Dolgin Jeff Carroll was in his mid-twenties, fresh out of the U.S. Army, when a genetic test confirmed his worst fear: He was going to develop Huntington’s disease. He had watched his mother’s illness for years; the tremors first, small enough to explain away, then the involuntary movements that looked almost like dancing. The test revealed that the same mutation that caused her disease lived in him: a stretch of three DNA letters in a gene called HTT, repeated over and over again dozens of times. Carroll himself was not sick yet. He would not get sick for many years. But the countdown had begun. In fact, it had likely been running all his life, deep inside vulnerable neurons in his brain. There, the mutant HTT gene was slowly growing longer, its internal repeats piling up toward a threshold that, once crossed, would tip the cell into disarray. The first outward signs of Huntington’s often begin with mood changes and subtle cognitive effects. The hallmark jerky movements come later. Eventually, and relentlessly, patients lose the ability to speak, swallow or move. Most people die within a decade or two of symptom onset. Huntington’s disease is rare, affecting roughly 1 in 20,000 people worldwide. Yet because each child of an affected parent has a 50 percent chance of inheriting the mutation, the disease can haunt families for generations. It had already claimed Carroll’s grandmother and would take his mother at age 54. Without a therapy capable of altering its course, Carroll — along with three of his five siblings who also inherited the mutation — seemed fated to follow his ancestors into an early grave. Carroll decided the only rational response was to become one of the scientists seeking ways to beat the disease. He was midway through his undergraduate studies when he learned, in 2003, that he carried the mutation. He pressed on, earning a Ph.D. and completing postdoctoral training before establishing his own research group devoted to understanding and slowing the disease stalking him from within. © Society for Science & the Public 2000–2026.

Keyword: Huntingtons
Link ID: 30332 - Posted: 07.18.2026

Ian Sample Science editor A man who was paralysed from the chest down in a swimming accident six years ago has been able to feed himself and drink from a cup thanks to a brain implant that bypasses his spinal cord injury. Keith Thomas of Massapequa, New York, could not lift his arms off his wheelchair when he agreed to trial the technology in 2021, but after surgery to implant electrodes in his brain and many months of training, he was able to move the limbs again. Researchers fitted Thomas with a brain-computer interface that not only helped him move his arms and hands, but also sent signals back to his brain to recreate the sensation of touch. He has since been able to feel his sister’s hand and the fur on his pet dog. Remarkably, the technology appears to have partly rewired Thomas’s nervous system, helping to restore some hand functions and sensations that remain even when the system is switched off. “For me this is an incredible moment,” said Prof Chad Bouton, whose team developed the technology at the Feinstein Institutes for Medical Research, the research arm of the New York healthcare provider Northwell Health. “For years, we have been wanting to really tackle the restoration of movement and the sense of touch and bring those together and we’ve also wanted to create lasting effects,” Bouton added. “I think we’re going to continue to see progress and I think it’ll be applicable to the millions of folks around the world who really need this technology.” Thomas was 42 when he broke his neck diving into a swimming pool in July 2020. He blacked out and regained consciousness to see a helicopter on the front lawn. He was immediately taken to hospital. “The next day I couldn’t even move,” he said. The following October, he joined a three-year clinical trial of what the researchers called a “double neural bypass”. It uses electrodes implanted into Thomas’s brain to detect when he wants to move his arms. The signals are then routed to his arms and hands to move them. © 2026 Guardian News & Media Limited

Keyword: Robotics
Link ID: 30331 - Posted: 07.18.2026